A new successful combination therapy with atenolol and prednisolone for Kasabach-Merritt syndrome
نویسندگان: ثبت نشده
چکیده مقاله:
Kasabach-merritt syndrome is a rare life-threatening syndrome associated with vascular tumors such as tufted angioma and kaposiform hemangioendothelioma. For this syndrome, there exist a few treatment modalities with variable results. For many years, corticosteroids have been employed in the first-line therapy. Nowadays, on the other hand, β blockers such as propranolol have been used owing to their acceptable efficacy and fewer side effects. In the present case report, atenolol combined with corticosteroid was, for the first time, prescribed for the treatment of the syndrome; a significant improvement was observed with no concomitant side effects.
منابع مشابه
Kasabach-Merritt syndrome.
Hemangiomas of infancy are usually congenital lesions. Occasionally they are associated with microangiopatbic bemolytic anaemia, thrombocytopenia, and a consumptive coagulopathy. This is most often associated with cavernous hemangiomas. Thrombocytopenia associated with giant cavernous hemangiomas was first noted by Kasabach and Merritt in 1940. As the primary mechanism of platelet destruction i...
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We describe two patients with haemangioma with thrombocytopenia (Kasabach-Merritt syndrome). Both were treated with corticosteroids without notable improvement. The first patient responded satisfactorily to radiotherapy, whereas the second showed a slow spontaneous resolution.
متن کامل[A case report of Kasabach-Merritt syndrome].
Kasabach Merritt syndrome (KMS) is an uncommon complication of large haemangioma in which there is thrombocytopenia and coagulopathy. We report a case of a new born male baby presented with a large haemangioma on the right upper extremity and his initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed as a case of KMS and treated with oral prednisolone. 1. Assoc...
متن کاملKasabach-Merritt syndrome: a case report.
Kasabach-Meritt syndrome is a combination of thromobocytopenia, hemolytic anemia, and acute or chronic consumptive coagulopathy in association with rapidly enlarging hemangioma. A male infant of 5 days was admitted in paediatric ward with this syndrome. The baby had ecchymotic patches over face and extremities and bleeding through umbilical stump. The child expired due to severe thrombocytopeni...
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Angiosarcomas are exceedingly rare tumors that are often difficult to diagnose. Exceptionally unusual is the presentation of these tumors with Kasabach-Merritt Syndrome, a curious form of intratumoral coagulation that can be impossible to distinguish from intravascular coagulation, which is more common. Instant recognition of this clinical association can help making a prompt diagnosis and time...
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عنوان ژورنال
دوره 20 شماره 4
صفحات 127- 130
تاریخ انتشار 2017-10-01
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